Maalinta Arthritis-ka Adduunka waa munaasabad lagu wacyi-gelinayo caafimaadka adduunka oo sannad walba la qabto 12-ka Oktoobar si loogu sameeyo wacyi-gelin ku saabsan cudurrada lafa-xanuunnada iyo murqaha, saameynta ay ku leeyihiin nolosha iyo in dadka lagu baro calaamadaha iyo tallaabooyinka ka hortagga iyo hagista baaritaanka hore ee cudurka si looga hortago dhibaatooyin kasta oo kale. .
Muhiimadda Maalinta Arthritis-ka Adduunka (WAD)
Arthritis-ku waa xanuun barar ah, kaas oo saameeya unugyada kala-goysyada ee ku wareegsan kala-goysyada, iyo unugyo kale oo isku xiran, taasoo keenta xanuun iyo qallafsanaan.In ka badan 100 nooc oo arthritis ah ayaa jira, laakiin inta badan waa osteoarthritis iyo rheumatoid arthritis.Ka warqab la'aanta iyo taageerada la'aanta awgeed, arthritis-ka iyo xaaladdiisa la xiriirta waxay naafeeyeen nolosha in badan oo adduunka ah.Ma jiro daawayn gaar ah oo loogu talagalay arthritis-ku, doorashada daawaynta way kala duwan tahay iyadoo lagu saleynayo noocyada, sidaa darteed waa lama huraan in la fahmo calaamadaha & astaamaha lana helo baaritaan hore si loo helo daawaynta habboon.
Nooca ugu caansan ee Arthritis
Noocyada ugu caansan waxaa ka mid ah osteoarthritis (OA), rheumatoid arthritis (RA), psoriatic arthritis (PsA), fibromyalgia iyo gout.Arthritis-ka iyo cudurrada la xidhiidha waxay siyaabo kala duwan u keeni karaan daciifnimo, xanuun nolosha beddela.
Rheumatoid arthritis-ka (RA) waa mid ka mid ah cudurrada wadajirka ah ee bararka ee ugu caansan, oo ku badan haweenka da'da dhexe.Inta badan waxa uu u muuqdaa sida dabadheeraad, summeeyeyaal, polyarthritis horumarsan.Marka laga soo tago inay saameeyaan kala-goysyada, waxaa jira astaamo badan oo ka baxsan articular, sida maqaarka, indhaha, wadnaha, sambabada, nidaamka dhiigga, iwm.
Baaxadda RA waa 0.5-1%, iyadoo haweeneyda saamiga ragga ay tahay 3: 1.4 ilaa 5 jeer ayay ka sareysaa dumarka da'doodu ka yar tahay 50 sano, laakiin 60 sano ka dib saamiga wuxuu noqonayaa qiyaastii 2 ilaa 1.Dadka qaba rheumatoid arthritis-ku waxay badanaa leeyihiin heerka borotiinka C-reactive (CRP), kaas oo muujin kara joogitaanka habka bararka ee jirka.Tijaabooyinka kale ee dhiigga ee caadiga ah waxay raadiyaan unugyada rheumatoid-ka (RF) iyo ka-hortagga unugyada difaaca jirka ee citrullinated peptide (anti-CCP).
RA(Rheumatoid arthritis-ka)
Rheumatoid arthritis-ku waa cillad barar joogto ah oo saameyn karta in ka badan oo kaliya xubnahaaga.Dadka qaarkood, xaaladdu waxay dhaawici kartaa noocyo badan oo hab-dhiska jirka ah, oo ay ku jiraan maqaarka, indhaha, sambabada, wadnaha iyo xididdada dhiigga.
Cudurka difaaca jirka, rheumatoid arthritis-ku wuxuu dhacaa marka habka difaacaagu si khalad ah u weeraro unugyada jidhkaaga.
Si ka duwan dhaawaca xirashada iyo jeexjeexa osteoarthritis, rheumatoid arthritis-ku wuxuu saameeyaa dahaarka kala-goysyadaada, taasoo keenta barar xanuun badan oo ugu dambeyntii keeni kara nabaad-guurka lafaha iyo qallafsanaanta wadajirka.
Anti-CCP Ka-hortagga-Cyclic Citrullinated Peptide Antibody
Anti-cyclic citrullinated peptide antibody (Anti-CCP): Waa jajab polypeptide ee borotiinka polyguanidine ee meertada ah oo inta badan waa antibody nooca IgG.Anti-cyclic citrullinated peptide antibodies si kedis ah ayey u siidaayaan B lymphocytes ee bukaanada qaba rheumatoid arthritis-ka (RA), halka B lymphocytes ee bukaanada qaba cudurrada kale iyo dadka caadiga ah aysan si kedis ah u soo saarin anti-cyclic citrullinated peptide antibodies.Sidaa darteed, waxay leedahay dareen sare oo gaar ah oo loogu talagalay rheumatoid arthritis-ka, waana tilmaame aad u gaar ah oo loogu talagalay ogaanshaha hore ee rheumatoid arthritis-ka.
Anti-CCP (Anti-cyclic citrullinated peptides) waa nooc ka mid ah autoantibody: antibody ka shaqeeya lidka ku ah unugyada caadiga ah ee jidhkaaga.Ka-hortagga CCP waxaa badanaa la soo saaraa marka aad qabtid rheumatoid arthritis-ka.Unugyadaan autoantibodies waxay bilaabaan inay beegsadaan oo ay weeraraan unug kale oo caafimaad qaba.
Tilmaamayaasha hore ee ogaanshaha cudurka rheumatoid arthritis-ka: unugyada difaaca jirka ee citrullinated anti-cyclic waxay soo muuqdaan 1-10 sano ka hor calaamadaha kiliinikada ee rheumatoid arthritis-ka, oo ku habboon baaritaanka jireed ee dadka caafimaadka qaba iyo ogaanshaha hore ee kooxaha khatarta sare leh.Hadda,waxaa la rumeysan yahay in dareenka anti-cyclic citrullinated peptide antibodies ee ogaanshaha rheumatoid arthritis waa 50% ilaa 78%, gaar ahaan 96%, iyo heerka togan ee bukaanada hore waxay gaari karaan 80%.
AehealthAnti-CCP Pdhaqan
Aehealth Anti-CCP (Anti-cyclic Citrullinated Peptide Antibody) Tijaabada Tirade Degdega ah waxay qabataa habka Immunofluorescence Assay.
Qalabka ka-hortagga-CCP ee cabbirka toosan ee ogaanshaha waa 10–500 U/ml;isku xidhka toosan ee udhaxeeya fiirsiga aragtida iyo fiirsashada la qiyaasay waxay gaadhi kartaa r≥0.990.Waxaa loo isticmaalaa falanqaynta Aehealth Lamuno X immunofluorescence si loo galbiyo ogaanshaha hore iyo qiimaynta daawaynta ee bukaanada lafa-beelka.
Ka-hortagga-CCP-ka-hortagga unugyada waxay la xiriiraan cabbirrada waxqabadka RA.
Ka-hortagga CCP-da waxay saadaaliyaan dhaawaca RA.
Waqtiga boostada: Oct-12-2022